787 research outputs found

    Choosing Online Partners in the Virtual World: How Online Partners Characteristics Affect Online Dating

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    This study used a deductive approach examining how online partners\u27 characteristics impacted online users in the following areas: (1) Appearance (including looks, height &weight), (2) Financial Prospects, (3) Age, (4) Self-disclosure, (5) values and beliefs. This study was focused on three important factors of online users: (1) Gender, (2) Age, and (3) Motive. Quantitative survey methods were used in this study. The research study used descriptive analysis, relationship analysis, Independent-Samples T-Test and ANOVA analysis to test the variables between groups, among groups, and between or among different variables. This research focused on 20 to 45 year olds because most people in this age group are involved in online dating services, and they had the basic technology (computer, Internet, online dating service) skills. The results show that different genders had different preferences in online partners\u27 weight and ambitions. The results show that age group 1 and group 2 had different preferences in online partners\u27 height and online partners\u27 value and belief. Age group 1 and group 3 had different preferences in online partners\u27 age. The results also show that different motives had different preferences regarding online partners height, financial prospects and age. There were four limitation of this study: (1) the researcher chose three popular chat rooms in Taiwan instead of all online dating websites. (2) There was no way to find out if the participants responded more than once because the survey was totally anonymous. (3) Time limit. (4) Participants in three specific online chat rooms were selected for inclusion in the sample, constituting a sample of convenience. Thus, the results may not be generalized to any online dating service or population. The contributions of this study are that there are no online dating research surveys conducted using quantitative methods that were not in English. This study was conducted in Taiwan using the Chinese language. In online dating research studies, most researchers used qualitative methods to analyze the topic. This paper used quantitative methods, sending the survey to online users in Taiwan. The results of this study in Taiwan and of those studies in the literature are very consistent

    Necrophilous Ants (Hymenoptera: Formicidae) in Diverse Habitats in Taiwan

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    Ants are a highly diverse group that not only are often strongly associated with certain habitat types, but also can be found on carcasses and, therefore, in crime scenes. In the present study, a survey of the necrophilous ants in Taiwan was conducted and a preliminary species checklist was provided for the first time. The aim of this study was primarily to offer information on Taiwanese ant species of forensic significance. A total of 50 ant species/morphospecies from 26 genera were collected from large scale regions in Taiwan using combination pig liver bait and pitfall traps, bringing the Taiwanese necrophilous ants up to 55 species from 33 genera within the known Taiwanese ant fauna of 288 species from 71 genera. Seventeen species found in this study are tramp or potentially exotic species, which often dominated the baits. Use of pitfall traps increased the diversity of ants collected relative to hand-collecting from the carcass, adding useful data. These necrophilous ants may play important roles in carcass decomposition and can be useful in reconstructing crime scenes, as certain ants are more common in certain habitat types. This checklist and accompanying habitat information of these ants is likely the first such comprehensive data in Taiwan applying ants to the field of forensic entomology

    (E)-N′-[1-(4-Chloro­phen­yl)ethyl­idene]-2-hydroxy­benzohydrazide

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    In the title compound, C15H13ClN2O2, the dihedral angle between the two benzene rings is 7.0 (1)°. An intra­molecular N—H⋯O hydrogen bond is present and inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains along [001]

    Role of glucose in the repair of cell membrane damage during squeeze distortion of erythrocytes in microfluidic capillaries

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    The rapid development of portable precision detection methods and the crisis of insufficient blood supply worldwide has led scientists to study mechanical visualization features beyond the biochemical properties of erythrocytes. Combined evaluation of currently known biochemical biomarkers and mechanical morphological biomarkers will become the mainstream of single-cell detection in the future. To explore the mechanical morphology of erythrocytes, a microfluidic capillary system was constructedin vitro, with flow velocity and glucose concentration as the main variables, and the morphology and ability of erythrocytes to recover from deformation as the main objects of analysis. We showed the mechanical distortion of erythrocytes under various experimental conditions. Our results showed that glucose plays important roles in improving the ability of erythrocytes to recover from deformation and in repairing the damage caused to the cell membrane during the repeated squeeze process. These protective effects were also confirmed inin vivoexperiments. Our results provide visual detection markers for single-cell chips and may be useful for future studies in cell aging

    Caffeic Acid Derivatives Inhibit the Growth of Colon Cancer: Involvement of the PI3-K/Akt and AMPK Signaling Pathways

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    The aberrant regulation of phosphatidylinositide 3-kinases (PI3-K)/Akt, AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (m-TOR) signaling pathways in cancer has prompted significant interest in the suppression of these pathways to treat cancer. Caffeic acid (CA) has been reported to possess important anti-inflammatory actions. However, the molecular mechanisms by which CA derivatives including caffeic acid phenethyl ester (CAPE) and caffeic acid phenylpropyl ester (CAPPE), exert inhibitory effects on the proliferation of human colorectal cancer (CRC) cells have yet to be elucidated

    Expression patterns and prognostic value of miR-210, miR-494, and miR-205 in middle-aged and old patients with sepsis-induced acute kidney injury

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    Septic patients suffer a ‘cytokine storm’ from proinflammatory cytokines, chemokines and other inflammatory mediators, resulting in acute kidney injury (AKI) and death. The purpose of the present study was to determine the expression patterns of microRNA-210 (miR-210), miR-494, and miR-205 in middle-aged and old patients with sepsis-induced AKI and to evaluate their association with patient prognosis. Serum blood urea nitrogen (BUN), creatinine (Cr) and cystatin C levels were determined in peripheral venous blood collected from 110 patients with sepsis-induced AKI and 110 healthy controls. The expression profile of miRNAs was analyzed by TaqMan low-density array (TLDA) in plasma samples from patients and controls. Association of miRNAs with prognosis and survival of patients was analyzed by Spearman’s rank correlation coefficient, Cox multivariate analysis, and ROC curve analysis. TILDA analysis showed 11 upregulated and 11 downregulated miRNAs in patients with sepsis-induced AKI. MiR-210 and miR-494 were the most upregulated and miR-205 was the most downregulated miRNA. High expression of miR-210 and miR-494 was positively correlated with BUN, Cr and cystatin C levels of patients, while low expression of miR-205 was negatively correlated. MiR-210 and miR-494 expression was significantly decreased and miR-205 expression was increased in survivors with sepsis-induced AKI (28-day survival, n = 68) vs. non-survivors (n = 42). BUN, Cr and miR-205 were independent risk factors for prognosis in sepsis-induced AKI. Our study showed the predictive value of miR-210, miR-494, and miR-205 in prognosis and survival of patients with sepsis-induced AKI. MiR-205 is an independent risk factor for sepsis-induced AKI and its decreased expression is associated with shorter patient survival

    A meta-analysis of the efficacy of 99Tc-MDP alone and in combination with 89SrCl2 in the treatment of bone metastases

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    Background and purpose: Bone metastatic tumor is a common disease of tumor bone metastasis, and the prognosis of patients is poor, with a variety of serious complications, including bone pain, fracture, spinal cord compression and other skeletal related events, affecting the quality of life of patients. At present, radionuclide therapy still has positive clinical effects in patients with bone metastasis, and it still plays an important role in relieving bone pain. This study aimed to evaluate the efficacy of technetium [99Tc] methylene diphosphonate injection (99Tc-MDP) alone or in combination with strontium chloride (89SrCl2) in the treatment of bone metastases. Methods: Databases were used to search for studies published between January 2000 and July 2022 on the efficacy of 99Tc-MDP in combination with 89SrCl2 and 99Tc-MDP alone in the treatment of bone metastases. All included literature was extracted and evaluated for quality, and Meta-analysis was performed using RevMan 5.3 software. Results: Twenty-seven publications met the inclusion criteria, and a total of 2564 patients were included in this study. The results demonstrated that 99Tc-MDP combined with 89SrCl2 improved bone pain relief (RR=1.22, 95% CI: 1.18-1.27, P<0.001) and bone metastasis healing (RR=1.35, 95% CI: 1.25-1.47, P<0.001). However, when compared with 89SrCl2 alone, it could not be concluded that 99Tc-MDP alone increased the rate of bone pain relief (RR=0.98, 95% CI: 0.90-1.06, P=0.57) and bone metastasis healing (RR=0.93, 95% CI: 0.82-1.06, P=0.27), and the difference between the two groups was not statistically significant. The common adverse effects of 99Tc-MDP treatment alone or in combination with 89SrCl2 were decreased leukocyte and platelet counts, however, the difference in the incidence of adverse effects between 99Tc-MDP treatment alone and in combination with 89SrCl2 was not statistically significant (89SrCl2 vs 99Tc-MDP in combination with 89SrCl2: RR=0.83, 95% CI: 0.53-1.30, P=0.42; 89SrCl2 vs 99Tc-MDP: RR=0.93, 95% CI: 0.76-1.13, P=0.45). Conclusion: 99Tc-MDP combined with 89SrCl2 treatment was effective in relieving pain in patients with bone metastases, and the bone pain relief rate and bone metastasis healing rate of 99Tc-MDP combined with 89SrCl2 treatment for bone metastases were better compared with the 89SrCl2 monotherapy group, with no significant increase in adverse reactions after typical dosing. Due to the limitations of the quality and quantity of literature included in this study, higher quality randomized controlled studies are needed
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